This publication emanates from an ESCAP research project to study the trends of the Asian and Pacific countries in harmonizing their national laws with the Convention on the Rights of Persons with Disabilities. It examines the extent to which reporting obligations have been fulfilled in a timely and substantive manner and the ways in which national human rights institutions and civil society organizations, in particular organizations of persons with disabilities, have been involved in that process. It further analyses good practices in harmonization, and challenges which have commonly arisen in relation to the implementation of the Convention in the Asian and Pacific region. The analytical regional overview draws from five country case studies prepared under the above mentioned ESCAP project, as well as other credible sources. This publication presents recommendations for the attention of ESCAP member States towards further enhancement of the effective harmonization of national legislation with the Convention and the implementation of the Convention.