The international division of labor involving East Asia has been forced to significantly change as a result of conflicts between the US and China. With regard to production, global value chains centered on China have been rapidly restructured. As for research and development, technological decoupling is underway, and the previously open innovation system is becoming semi-closed. Furthermore, skepticism is growing about the feasibility of an international division of labor among countries with disparate economic systems. Based on the research findings in our book on this topic, this column analyzes the impacts of US?China economic conflicts on East Asian economies and explains the responses of relevant countries and regions.