The brief highlights the substantial presence of Indigenous Peoples in Asia and the Pacific and the importance of traditional knowledge and genetic resources for climate action, food security, and medicine, as well as language diversity and cultural heritage. It explains the shortfalls of existing FTAs and why they should be based on informed consent, equitable benefit sharing, and full source disclosure in patents. It details how some FTAs have included traditional knowledge and genetic resources and shows how trade deals can help Indigenous Peoples benefit from greater regional cooperation.