Universities play an important role in driving innovation and economic growth within their own regions across England and Wales. By engaging with local partners, they help address societal challenges and support regional development. Yet, integrating a territorial dimension in research, innovation and engagement agendas can be challenging. The report, The Geography of Higher Education in England and Wales, draws on insights from the OECD Entrepreneurship Education Collaboration and Engagement (EECOLE) platform. Focusing on the National Civic Impact Accelerator (NCIA), established by the Civic University Network, it explores how universities are aligning their research and innovation efforts with regional priorities to strengthen entrepreneurial ecosystems. The report also highlights the importance of stronger partnerships with local stakeholders, including SMEs, to enhance the impact of the NCIA on regional innovation and prosperity.