This paper presents a tailored set of 24 subnational indicators to be used as a tool to inform and enhance evidence-based policy development and sustainable destination management in Portugal. It builds on existing frameworks and good practices at an international, national and regional level. The indicator selection was informed by key policy priorities identified in national and regional tourism strategies as well as through stakeholder consultations. The paper highlights avenues for future development to refine indicator methodologies and close existing data gaps on priority policy issues.