Public discussion has largely focused on the effects of tech policy on platforms or casual users, while relatively little attention has been paid to entrepreneurial types of users or those who have leveraged these platforms beyond mere entertainment purposes. In this paper I explore the effects that some of the most debated issues―such as proposed policy changes in the areas of antitrust, Section 230 of the Communications Decency Act of 1934 and content moderation, and data privacy―could have on this unique group of users. I focus only on the effects of changes to government regulation and not policies regarding data or content that might be determined at a firm or individual level. Finally, I examine how entrepreneurial users responded to the proposed Children’s Online Privacy Protection Act (COPPA) policy changes, which they believed could have significant effects on their entrepreneurial opportunities on platforms such as YouTube, to illustrate how these users are uniquely affected and how they have devised novel responses to potential tech policy changes.