The study examines how the Dominican Republic is strengthening its position within global value chains for medical devices, semiconductors, and nickel. Building on established manufacturing and mining capabilities, the country has attracted significant multinational investment and demonstrated robust export growth, particularly in advanced manufacturing sectors. Recent policy initiatives and effective public-private collaboration are enabling the Dominican Republic to move into higher-value segments, such as semiconductor assembly and sustainable nickel sulfate production for clean technologies. Continued advancement will depend on further developing human capital, infrastructure, and regulatory frameworks to enhance competitiveness, resilience, and sustainable development in these strategic industries.