The United States is currently experiencing the most significant rethinking of American foreign policy in 80 years. This will have extensive implications for Pacific Islanders, especially the people of Micronesia who depend on the United States to abide by longstanding agreements that ensure regional security and prosperity. But the exact ramifications remain highly uncertain, given the Trump administration’s lack of a clear and coherent approach to the region. This essay attempts to decipher how dynamics are shifting in the Indo-Pacific and what this will mean for Pacific Islanders in particular.